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    Buy 2-Deoxy-D-galactose (CAS 1949-89-9), an analog of hexose that inhibits fucosylation, from Santa Cruz. Molecular Formula: C6H12O5, Molecular Weight: 164.2

    2-Deoxy-D-glucose ≥99% (GC), crystalline | Sigma-Aldrich

    2-Deoxy-D-Glucose (2-Deoxyglucose) is a glucose analog that inhibits glycolysis via its actions on hexokinase, the rate limiting step of glycolysis. It is phosphorylated by hexokinase to 2-DG-P which can not be further metabolized by phosphoglucose isomerase. This leads to the accumulation of 2-DG-P in the cell and the depletion in cellular ATP.

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    Looking for online definition of Deoxyglucose in the Medical Dictionary? Deoxyglucose explanation free. What is Deoxyglucose? Meaning of Deoxyglucose medical term. What does Deoxyglucose mean? . 2-deoxy-d-glucose (redirected from Deoxyglucose) 2-deoxy-d-glucose [de-ok´sĭ-gloo´kōs]

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    2-Deoxy-D-glucose | Sigma-Aldrich

    In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product.

    Tritiated 2‐deoxy‐D‐glucose: A high‐resolution marker for .

    Jan 01, 1984· Tritiated 2‐deoxy‐D‐glucose: A high‐resolution marker for autoradiographic localization of brain metabolism. Ronald P. Hammer Jr. Laboratory of Neurophysiology, National Institute of Mental Health, Bethesda, Maryland 20205. Search for more papers by this author. Miles Herkenham.

    The Glycolytic Inhibitor 2-Deoxyglucose Activates Multiple .

    Recent molecular studies indicate that aerobic glycolysis plays an important role in tumorigenesis and is a valid target for cancer therapy. Although 2-deoxyglucose (2-DG) is well characterized as a glycolytic inhibitor, we recently discovered that it activates a prosurvival oncoprotein, AKT, through PI3K.

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    Deoxyribose | 2-Deoxy-D-ribose | 533-67-5 | Carbosynth Product

    Scheme 4. Uses in natural product synthesis have also been disclosed, for example Sasaki and co-workers have synthesized the polycyclic ether natural product (-)-brevenal in a lengthy sequence from 2-deoxy-D-ribose, and Holmes and Burton have reported its use in the formal synthesis of the medium ring ether ent-obtusenyne.

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    154-17-6 | 2-Deoxy-D-glucose | ChemScene llc

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    APExBIO - 2-Deoxy-D-glucose|Glycolysis inhibitor|CAS# 154-17-6

    2-Deoxy-D-glucose (2DG), glucose analogue, is a competitive glycolytic inhibitor [1] [2] [3]. Cytotoxicity assays displayed IC50 values of 2DG in KIT-positive GIST cell lines between 0.5μM (GIST882 cell line) and 2.5μM (GIST430 cell line) [4]. Glycolysis

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    2-deoxy-d-glucose | definition of 2-deoxy-d-glucose by .

    2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells. Optimization of cancer therapy: Part I--Inhibition of repair of x-ray induced potentially lethal damage by 2-deoxy-D-glucose in Ehrlich-ascites tumour cells.

    2-Deoxy-D-ribose 97% | Sigma-Aldrich

    2-Deoxy-D-ribose 97% Synonym: 2-Deoxy-D-arabinose, 2-Deoxy-D-erythropentose, Thyminose CAS Number 533-67-5. Empirical Formula (Hill Notation) C 5 H 10 O 4. Molecular Weight 134.13 . Beilstein/REAXYS Number 1721978 . EC Number 208-573-0. MDL number MFCD00135904. PubChem Substance ID 24847465

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    2-Deoxy-D-Glucose - 154-17-6 (China Manufacturer .

    2-Deoxy-D-Glucose 154-17-6 - 2-Deoxy-D-Glucose Products Made In China, China Manufacturer. 2-Deoxy-D-Glucose 2-Deoxy-D-Glucose CAS 154-17-6 Molecular Structure 2-deoxy-d-glucose;2-deoxy-d-arabino-hexose; d-arabino-2-deoxyhexose; Molecular Formula: C6H12O5 Molecular Weight: 164.16 CAS Registry Number: 154-17-6 Standard: Enterprise standard Packing:500g/bag Character: …

    2-Deoxy-D-glucose (2-Deoxy-D-arabino-hexose) | Hexokinase .

    The effect of 2-DG on cell growth is determined by evaluating the number of adherent cells. Briefly, MCF-7 cells are plated at 3×10 4 cells per well in flat-bottomed 96-well plates in 100 μL of culture medium under the culture conditions. After 24 hours, cells are fed with fresh medium including 2-Deoxy-D-glucose at doses of 0, 4, 8, or 16 mM.

    2-Deoxy-D-Glucose | ABIN3045577 - antibodies-online

    Search, Find and Buy Antibodies, ELISA Kits and Proteins. . 2-Deoxy-D-Glucose is a glucose analog that has long been known to act as a competitive inhibitor of glucose metabolism. Upon transport into the cells, 2-DG is phosphorylated by hexokinase to 2-DG-P. However, unlike G-6-P, 2-DG-P cannot be further metabolized by phosphohexose .

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    Deoxy-D-glucose, 2-[1,2-3H(N)] - NET549250UC | PerkinElmer

    2-deoxy-D-glucose, labeled at the 1,2 position with tritium. This glucose analog is readily transported into most cells and cannot be further metabolized, and is commonly used in glucose uptake assays.

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    The Effects of 2-Deoxyglucose on the Growth and Metabolism .

    The glucose analogue, 2-deoxy-n-glucose, has been found to inhibit glycolysis and the growth of yeast (1, 2) and various animal tissues (3-7). It is phosphorylated by hexokinase (8), but is not believed to be further metabolized. Wick et al. (9) have reported that deoxyglucose B-phosphate competitively in-

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    Abstract. By using 2-deoxy-D-glucose, selection of different mutants of Aspergillus oryzae PTCC 5164, which were produced by random mutagenesis by u.v. radiation, nitrous acid and N-methyl-N′-nitro-N-nitrosoguanidine (MNNG), was studied. 2-Deoxy-D-glucose, a well-known antimetabolite, was used to isolate derepressed mutants.The mutational and lethal effects of these mutagens on conidia of A .

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    2-Deoxy-D-glucose | C6H12O5 | ChemSpider

    A 2-deoxy-<stereo>D</stereo>-glucose that is <stereo>D</stereo>-glucopyranose in which the hydroxy group at position 2 has been replaced by a hydrogen. ChEBI CHEBI:84755: Bio Activity: 2-Deoxy-D-Glucose (2-Deoxyglucose) is a glucose analog that inhibits glycolysis via its actions on hexokinase, the rate limiting step of glycolysis.

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