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    2-Deoxy-D-glucose (2DG), glucose analogue, is a competitive glycolytic inhibitor [1] [2] [3]. Cytotoxicity assays displayed IC50 values of 2DG in KIT-positive GIST cell lines between 0.5μM (GIST882 cell line) and 2.5μM (GIST430 cell line) [4]. Glycolysis

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    Sep 06, 2017· WP1122 is a 2-deoxy-D-glucose prodrug in pre-clinical development for glioblastoma Leave a reply The Warburg Effect is a universal feature of cancer ; it describes the phenomenon whereby cancer cells preferentially use glucose for anaerobic glycolysis, as opposed to …

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    Description: Storage:This product shall be sealed to preserve. This product is crystallize solid.Soluble in water and ethanol.The α type's melting point is 134~136℃.The β type's melting point is 142~144℃.Used in biochemical study.

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    References. References are publications that support the biological activity of the product. Kang and Hwang (2006) 2-deoxyglucose: an anticancer and antiviral therapeutic, but not any more a low glucose mimetic. Life Sci. 78 1392 PMID: 16111712 Maher et al (2004) Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-D-glucose in tumor cells treated under hypoxic vs aerobic conditions.

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